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Platforms Overview Biosystem Platforms Mantarray™ – 3D Tissue Contractility Analysis NEW! Mantarray Mini Plates – Fewer Cells. More Data. Nautilai™ – Voltage & Calcium Imaging Stingray™ – Maturation of 3D Engineered Tissues NanoSurface™ Plates – HCI Plates for Structural Maturation Data Analytics Platforms Pulse™ – High-Throughput Video Contractility Analysis Software
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PLATFORMS Platforms Overview Biosystem Platforms Mantarray™ – 3D Tissue Contractility Analysis NEW! Mantarray Mini Plates – Fewer Cells. More Data. Nautilai™ – Voltage & Calcium Imaging Stingray™ – Maturation of 3D Engineered Tissues NanoSurface™ Plates – HCI Plates for Structural Maturation Data Analytics Platforms Pulse™ – High-Throughput Video Contractility Analysis Software MODELS Models Overview Applications Skeletal Muscle Models Cardiac Models Disease Models Cells & Media NEW! Curi Bio Cardiac Media MantaReady™ 3D Skeletal Muscle Tissue Media MantaReady™ Skeletal Muscle Myoblasts Celogics Celo.Cardiomyocytes PARTNERSHIPS Curi Engine Services Curi Engine™ Services RESOURCES Product Literature Product Literature Application Notes Peer-Reviewed Publications & Posters Webinars Videos Knowledge Base ABOUT Company Company News Events – Workshop World Tour Distributors Careers
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Peer-Reviewed Publications

 
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A Nanotopography Approach for Studying the Structure-function Relationships of Cells and Tissues
A Nanotopography Approach for Studying the Structure-function Relationships of Cells and Tissues

Kshitiz, Junaid Afzal, Sang-Yeob Kim & Deok-Ho Kim, Cell Adhesion & Migration, 9:4, 300-307, DOI, Publication Date: 2015 (Link To Paper)

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NanoSurface PlatesArianna KieserMay 26, 2015T Cells, ECM
Combined Effects of Substrate Topography and Stiffness on Endothelial Cytokine and Chemokine Secretion

Hyeona Jeon et al. ACS Appl. Mater. Interfaces 2015, 7, 8, 4525-4532, Publication Date: February 6, 2015 (Link To Paper)

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Endothelial Cells, NanoSurface PlatesArianna KieserFebruary 6, 2015Human Endothelial Cells
Enhanced Chondrogenic Differentiation of Dental Pulp Stem Cells Using Nanopatterned PEG-GelMA-HA Hydrogels

Cameron L. Nemeth et al. Tissue Engineering Part A VOL. 20, NO. 21-22, Publication Date: 25 Jun 2014 (Link To Paper)

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Stem Cells, NanoSurface PlatesArianna KieserJune 25, 2014DPSC
Fabrication of Poly(ethylene Glycol): Gelatin Methacrylate Composite Nanostructures with Tunable Stiffness and Degradation for Vascular Tissue Engineering

Peter Kim et al. Biofabrication, Volume 6, Number 2, Date Published: 10 April 2014 (Link To Paper)

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Endothelial Cells, NanoSurface PlatesArianna KieserApril 10, 2014HUVECs
Synergistic Effects of Matrix Nanotopography and Stiffness on Vascular Smooth Muscle Cell Function

Somali Chaterji et. al. Tissue Engineering Part A Vol. 20, No. 15-16 (Link To Paper)

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Muscle Cells, NanoSurface PlatesArianna KieserApril 1, 2014vSMC
Spatial Control of Adult Stem Cell Fate Using Nanotopographic Cues

Eun Hyun Ahn et al. Biomaterials, 35(8), Pages 2401–2410(2014) (Link To Paper)

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Stem Cells, NanoSurface PlatesArianna KieserMarch 31, 2014hMSC
Thermoresponsive Nanofabricated Substratum for the Engineering of Three-Dimensional Tissues with Layer-by-Layer Architectural Control
Thermoresponsive Nanofabricated Substratum for the Engineering of Three-Dimensional Tissues with Layer-by-Layer Architectural Control

Alex Jiao et al. ACS Nano 2014, 8, 5, 4430-4439, Publication Date: March 15, 2014 (Link To Paper)

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Muscle Cells, NanoSurface PlatesArianna KieserMarch 15, 2014
Nanopatterned Muscle Cell Patches for Enhanced Myogenesis and Dystrophin Expression in a Mouse Model of Muscular Dystrophy

Hee Seok Yang et al. Biomaterials, Volume 35, Issue 5, February 2014, Pages 1478-1486 (Link To Paper)

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Muscle Cells, NanoSurface PlatesArianna KieserFebruary 28, 2014Mouse Muscle Cells
Nanotopography-Guided Tissue Engineering and Regenerative Medicine

Hong Nam Kim et al. Advanced Drug Delivery Reviews ,65(4), 536–558(2013) (Link To Paper)

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Muscle Cells, Endothelial Cells, NanoSurface PlatesArianna KieserApril 30, 2013Cardiac Tissue, Bone Tissue, Skin Tissue, Ligament Cells, Tendon Cells, Skeletal Muscle Cells, Blood Vessels, Neurons
Nanopatterned Cardiac Cell Patches Promote Stem Cell Niche Formation and Myocardial Regeneration
Nanopatterned Cardiac Cell Patches Promote Stem Cell Niche Formation and Myocardial Regeneration

Deok-Ho Kim et al. Integr. Biol., 2012,4, 1019-1033 (Link To Paper)

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Stem Cells, NanoSurface PlatesArianna KieserAugust 13, 2012Cardiosphere-derived Stem Cells
Regulation of Brain Tumor Dispersal by NKCC1 Through a Novel Role in Focal Adhesion Regulation
Regulation of Brain Tumor Dispersal by NKCC1 Through a Novel Role in Focal Adhesion Regulation

Tomas Garzon-Muvdi et al. PLoS Biology, vol. 10, pp. e1001320, 2012. (Link To Paper)

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NanoSurface PlatesArianna KieserMay 1, 2012Glioma Tissue
Matrix Nanotopography as a Regulator of Cell Function

Deok-Ho Kim et al. JCB, 197(3), 351-360 Publication Date: 2012 (Link To Paper)

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Fibroblast Cells, Stem Cells, NanoSurface PlatesArianna KieserApril 30, 2012NIH 3T3, CHO, hMSC
Quantitative Analysis of the Combined Effect of Substrate Rigidity and Topographic Guidance on Cell Morphology

JinSeok Park et al. IEEE Transactions on NanoBioscience Volume: 11 , Issue: 1 , March 2012 (Link To Paper)

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NanoSurface PlatesArianna KieserSeptember 8, 2011CHO
Synergistically Enhanced Osteogenic Differentiation of Human Mesenchymal Stem Cells by Culture on Nanostructured Surfaces with Induction Media

Mi-Hyeon Yu et al. Biomacromolecules, 12;11(7):1856-62 (2010) (Link To Paper)

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Stem Cells, NanoSurface PlatesArianna KieserJune 22, 2010hMSC
Nanoscale Cues Regulate the Structure and Function of Macroscopic Cardiac Tissue Constructs

Deok-Ho Kim et al. Proc Natl Acad Sci U S A, 107(2):565-70(2010) (Link To Paper)

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Muscle Cells, NanoSurface PlatesArianna KieserJanuary 12, 2010NRVMs
Mechanosensitivity of Fibroblast Cell Shape and Movement to Anisotropic Substratum Topography Gradients

Deok-Ho Kim et al. Biomaterials, 30(29):5433-44(2009) (Link To Paper)

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Fibroblast Cells, NanoSurface PlatesArianna KieserOctober 31, 2009NIH 3T3
Guided Cell Migration on Microtextured Substrates with Variable Local Density and Anisotropy

Deok-Ho Kim et al. Adv Funct Mater., 19(10): 1579–1586(2009) (Link To Paper)

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Fibroblast Cells, NanoSurface PlatesArianna KieserFebruary 6, 2009NIH 3T3
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Mantarray™
3D Engineered Tissue Contractility Analysis

Cytostretcher™
Cell Stretching Instruments

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Structural Maturation of Cardiac & Skeletal Muscle Cultures

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Utilize the Curi Engine™ for:

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