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Pulse

Curi Bio’s Suite of Intuitive Contractile Tissue Software Solutions

 
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High-throughput Contractility Video Analysis

Pulse makes it easy to perform quantitative studies with stem cell-derived and primary cardiomyocytes. Capabilities include:

  • Calcium Measurement with Image Intensity Analysis

  • Contractility & Beat Measurement with Correlation Analysis & Optical Flow

  • Compare Post-Analysis Results with Ease

The desktop software (for Windows or MacOS) enables high-throughput analysis via batch-upload of videos on 96 and 384-well plate experiments.

 
 

High-throughput Analysis of 3D Engineered Tissues

A. Force Frequency, B. Rate of Contraction/Systole, C. Rate of Relaxation/Diastole, D. Time to Max Twitch (Peak), E. Maximal Twitch Amplitude, F. Full Width at Half Max

 
 

Optical Mapping of Voltage and Calcium for Clinically-Relevant Screening and Discovery

Nautilai enables high-throughput analysis of electrophysiology and calcium transients all on a standard SBS-compliant plate in 2D and 3D cell formats.

Information-rich Output Enables Multiple Applications:

  • Calcium Flux

  • Cardiomyocyte Screening

  • Cardiotoxicity

  • Potassium Assays

  • Ion Channel