Advance Your 3D Skeletal Muscle Tissue Experiments
Stronger Tissues
Engineered muscle tissues (EMTs) develop stronger contractile forces when cultured in Curi Bio’s medium compared to conventional medium (DMEM high glucose, 2% horse serum, IGF-1) described in literature (over 1000 citations) to promote in vitro myoblast differentiation and fusion. Twitch and tetanic forces are 4-5 times stronger in primary and iPSC-derived muscle constructs.
Faster Kinetics
EMTs display faster contraction and relaxation times, suggesting improved health and performance of muscle constructs compared to tissues cultured in conventional medium. Delayed contractile kinetics may indicate impaired function in normal and diseased tissues.
Greater Longevity
EMTs are stronger and remain contractile for over 63 days in culture, allowing for broad experimental timescales. Test your therapeutic over months or discover disease phenotypes that may present during late stages of in vitro development.
Unmatched Performance
EMTs show dramatically improved morphology and function over both the leading competitor’s medium and conventional medium. Curi Bio’s proprietary media minimizes excessive passive tension to promote ideal compaction and homeostasis in 3D muscle constructs during development to produce tissues with robust contractile function.
Day 8 – 3D iPSC Engineered Muscle Tissues
Available Skeletal Muscle Tissue Media Products
Curi Bio’s Serum-free MantaReady Medium Kits Are Designed for All Stages of Muscle Development and Maturation
Reserve Your Skeletal Muscle Medium
Fill out the form below to order/reserve your medium. After you submit, a Curi Bio team member will be in touch ASAP to communicate further details.
3D iPSC Skeletal Muscle Media Kits
Differentiation Kit (Day 0-10)
Maintenance Kit (Day 10+)
3D Primary Skeletal Muscle Media Kits
Differentiation Kit (Days 0-7)
Maintenance Kit (Day 7+)
Learn More About MantaReady™
Curi Bio’s MantaReady suite of products adds efficiency to your 3D muscle tissue experiments.
If you are interested in learning more about how MantaReady products can accelerate your research, please contact us to arrange a conversation with our team of experts.